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According to Tomita and co-author Dr Jennifer Manuel of New York University, although the underlying mechanisms are unclear, the hypothesis is based on the premise that prolonged nicotine alters the neurochemicals in the regulatory systems which may in turn make it difficult to regulate stress or emotions

This is a neural network responsible for feelings of pleasure, satisfaction, and enjoyment

In fact, while tobacco products contain specific nitrosamines, herbal combinations contain other diverse phytochemicals such as saponins or terpenes

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Of the former smokers, 319 had smoked less than 32 pack years