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Cigarette smoke or cigarette smoke extract (CSE), which is used in cell culture experiments, promotes several pathophysiological processes associated with AMD in RPE and surrounding tissues, including oxidative stress, inflammation, cell senescence, and neovascularization resulting in a significantly increased risk to develop AMD [4, 6, 9, 28]

7-8 ) as there are differences in methodology, data and the number of diseases covered

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These numbers, write the studys authors, show that people who have used e-cigarettes to completely quit smoking are more and more likely to be interested in non-tobacco and non-menthol flavors