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In a new study, researchers sought to tease out the independent effect of each risk factor on head and neck cancer development

Over time, smokers develop tolerance, requiring more cigarettes to achieve the same effect, and when they try to quit, they face withdrawal symptoms like irritability, anxiety, insomnia, and intense cravings

They may also recommend the use of hormone replacement therapy (HRT) if deemed appropriate

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While for heavy users of both alcohol and tobacco, this risk increases to up to 35 times greater

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