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On the one hand, Akkermansia muciniphila enhances the junction strength between intestinal epithelial cells by regulating the expression of tight junction proteins, such as ZO-1, Occludin, and Claudin-1, to attempt to repair the disrupted intestinal barrier (Liu et al., 2023)

ChoRE is a specific DNA sequence found in the regulatory regions of key genes implicated in glucose metabolism and DNL (Yu et al

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This astrocyte-neuron metabolic coupling sustains continuous aerobic glycolysis and offers a potential treatment strategy for AD

however, the myocardium exhibits a marked reduction in copper content [168]

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