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Under acidic and glutathione-rich conditions, the nanoplatform disassembles, releasing oxygen, manganese ions, and ART to alleviate tumor hypoxia

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We first tested if PSR-1 puncta could be affected by 1, 6-Hexanediol (1,6-HD), an aliphatic alcohol that has been routinely used to disrupt multivalent hydrophobic protein-protein interactions to disassemble phase-separated droplets 60,61

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