In parallel, the smoking-induced CO binds with haemoglobin and myoglobin, reduces arterial O2 blood saturation, and compromises the efficiency of respiratory enzymes, resulting in dysfunction of the O2 production, transportation and delivery system, especially during exercise
Two of these studies reported that almost 90% of respondents did not consider themselves hooked or dependent on waterpipe smoking [21, 56]
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Impact of nicotine replacement therapy on smoking behavior