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Supplementary material The Supplementary Material for this article can be found online at: References 1 SunHSaeediPKarurangaSPinkepankMOgurtsovaKDuncanBBet al

25-Hydroxycholesterol (H1015), cholesterol (C3045), AY9944 (190080), MCD (332615), 4-CBA (135585), Uridine (U3003), methylcellulose (M0512) were purchased from Sigma

Given the central involvement of redox signaling in immune cell activation and inflammatory responses, SRXN1 may play a regulatory role in shaping immune cell behavior, particularly in macrophages