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Side Effects and Safety Considerations Shared Side Effects Both peptides can cause similar adverse effects, most of which are gastrointestinal and often decrease over time

If a patient is already on levothyroxine for hypothyroidism, their endocrinologist may adjust the dose 6 to 8 weeks after significant weight loss stabilizes

I have had a REALLY HARD time losing any weight since high school

It enhances insulin secretion, reduces glucagon secretion, and slows gastric emptying, which collectively help lower blood glucose levels

But since the drugs also curb hunger signals, doctors may prescribe these drugs including popular brands Wegovy and Ozempic to help patients lose weight

All adverse event data in this article comes from two sources: the Phase 2 trial published in the New England Journal of Medicine (Jastreboff et al., 2023) and the TRIUMPH Phase 3 program data presented at medical conferences