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[8] Protein binding is also not a concern at typical doses

B12 helps keep nerves and blood healthy

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Under quiescent conditions, cytosolic Nrf2 directly binds to Kelch-like ECH-associated protein 1 (Keap1), a substrate adapter protein for the Cul3E3ligase complex, resulting in rapid degradation of Nrf2 (Ulasov et al., 2022)

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