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In 1916, Chesterfield became the first cigarette to use a moisture-proof wrapper, which helped maintain the freshness of the tobacco

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In this line, results from GCMS and HPLC analyses indicated that cinnamaldehyde (CAD) and 2-methoxycinnamaldehyde, but not dipropylene glycol or vanillin, were mainly responsible for the high cytotoxicity of cinnamon-flavoured e-liquids [80]

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Leaders of Lorillard, which sells the popular Newport brand of menthol cigarettes, could not be reached